2 edition of Citalopram use in pregnancy: A prospective comparative evaluation of pregnancy and fetal outcome. found in the catalog.
Citalopram use in pregnancy: A prospective comparative evaluation of pregnancy and fetal outcome.
Written in English
The effect of citalopram, a selective serotonin reuptake inhibitor, on pregnancy outcome was investigated.Women who took citalopram during pregnancy were matched to a disease-group and to a non-teratogen group of women. Matching criteria included maternal (+/-2 yrs) and gestational (+/-2 wks) age. A telephone follow-up was conducted following delivery.There were 132 women in each group. One hundred and fourteen (86%) women on citalopram had live births, 14 (11%) had spontaneous abortions, 2 (1.5%) had elective terminations and 2 (1.5%) experienced still births. Fetal survival rates, mean birth weights, duration of pregnancies, and major malformations were not statistically different between the groups. There was a relative risk (RR) of 4.2 (CI 95%: 1.6-11.1) in neonates exposed to citalopram close to term to be admitted to the special-care nurseries as compared to the unexposed infants.Late pregnancy use of citalopram was associated with increased risk of poor neonatal adaptation syndrome.
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